This brand name is authorized in United States.
The drug DECNUPAZ contains one active pharmaceutical ingredient (API):
1
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UNII
L15LO3W1XX - PIVEKIMAB SUNIRINE
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Pivekimab sunirine is a CD123 (alpha-subunit of the interleukin-3 receptor)-directed antibody-drug conjugate (ADC). The antibody is a humanized anti-CD123 IgG1. Pivekimab sunirine binds to CD123 expressing cells and upon intracellular processing releases a cell membrane-permeable payload, FGN849, leading to DNA alkylation, single-strand DNA breaks, apoptosis, and cell death. The payload, FGN849, is a member of the indolinobenzodiazepine pseudodimer (IGN) class of cytotoxic molecules. Pivekimab sunirine exhibited antitumor activity in in vitro and in vivo models of BPDCN. |
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Below package inserts are available for further reading:
| Document | Type | Information Source | |
|---|---|---|---|
| DECNUPAZ Powder for solution for injection | MPI, US: SPL/PLR | FDA, National Drug Code (US) |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| US | FDA, National Drug Code | 0074-0282 |
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