DECNUPAZ

This brand name is authorized in United States.

Active ingredients

The drug DECNUPAZ contains one active pharmaceutical ingredient (API):

1
UNII L15LO3W1XX - PIVEKIMAB SUNIRINE
 

Pivekimab sunirine is a CD123 (alpha-subunit of the interleukin-3 receptor)-directed antibody-drug conjugate (ADC). The antibody is a humanized anti-CD123 IgG1. Pivekimab sunirine binds to CD123 expressing cells and upon intracellular processing releases a cell membrane-permeable payload, FGN849, leading to DNA alkylation, single-strand DNA breaks, apoptosis, and cell death. The payload, FGN849, is a member of the indolinobenzodiazepine pseudodimer (IGN) class of cytotoxic molecules. Pivekimab sunirine exhibited antitumor activity in in vitro and in vivo models of BPDCN.

 
Read more about Pivekimab sunirine

Medication package inserts

Below package inserts are available for further reading:

Document Type Information Source  
 DECNUPAZ Powder for solution for injection MPI, US: SPL/PLR FDA, National Drug Code (US)

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
US FDA, National Drug Code 0074-0282

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