This brand name is authorized in Austria, Australia, Canada, Cyprus, Estonia, Spain, Finland, France, Croatia, Ireland, Israel, Japan, Lithuania, Netherlands, New Zealand, Poland, Romania, Turkey, United Kingdom, South Africa
The drug DUODOPA contains a combination of these active pharmaceutical ingredients (APIs):
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1
Levodopa
UNII 46627O600J - LEVODOPA
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According to the current understanding, the symptoms of Parkinson’s disease are related to depletion of dopamine in the corpus striatum. Dopamine does not cross the blood-brain barrier. Levodopa, the precursor of dopamine, crosses the blood brain barrier and relieves the symptoms of the disease. |
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2
Carbidopa
UNII MNX7R8C5VO - CARBIDOPA
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Carbidopa is a peripheral aromatic amino acid decarboxylase inhibitor. It prevents metabolism of levodopa to dopamine in the peripheral circulation, ensuring that a higher proportion of the dose reaches the brain, where dopamine exerts its therapeutic effects. A lower dose of levodopa can be used when it is coadministered with carbidopa, reducing the incidence and severity of peripheral side effects. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N04BA02 | Levodopa and decarboxylase inhibitor | N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BA Dopa and dopa derivatives |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: AU | Pharmaceutical Benefits Scheme | Identifier(s): 11910W, 11913B, 11919H, 8970D, 9743T, 9744W |
| Country: CA | Health Products and Food Branch | Identifier(s): 02292165 |
| Country: EE | Ravimiamet | Identifier(s): 1192867 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 66547 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 095314 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 64757532 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 101620 |
| Country: IE | Health Products Regulatory Authority | Identifier(s): 89058 |
| Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 6662 |
| Country: JP | 医薬品医療機器総合機構 | Identifier(s): 1169101S1020 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1021102 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 77569 |
| Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 16907 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100150430 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W60962001 |
| Country: TR | İlaç ve Tıbbi Cihaz Kurumu | Identifier(s): 8680656080063 |
| Country: ZA | Health Products Regulatory Authority | Identifier(s): 44/5.4.1/0456 |
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