HERNEXEOS

This brand name is authorized in United States.

Active ingredients

The drug HERNEXEOS contains one active pharmaceutical ingredient (API):

`1`	Zongertinib UNII `DRH7R67UVL` - ZONGERTINIB
	Zongertinib is a kinase inhibitor of human epidermal growth factor receptor 2 (HER2). In vitro, zongertinib inhibited phosphorylation of HER2, downstream signaling of HER2 (phosphorylation of ERK), and proliferation of lung cancer cells harboring HER2 tyrosine kinase domain activating mutations. In vivo, zongertinib demonstrated anti-tumor activity in mouse xenograft models of NSCLC harboring HER2 tyrosine kinase domain activating mutations.
	Read more about Zongertinib

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
HERNEXEOS Film-coated tablet	MPI, US: SPL/PLR	FDA, National Drug Code (US)

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
US	FDA, National Drug Code	0597-9257

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