This brand name is authorized in United States. It is also authorized in Austria, Lithuania.
The drug LOQTORZI contains one active pharmaceutical ingredient (API):
1
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UNII
8JXN261VVA - TORIPALIMAB
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Toripalimab is a humanised IgG4 monoclonal antibody that binds to the PD-1 receptor and blocks its interaction with PD-L1 and PD-L2, releasing PD-1 pathway-mediated inhibition of the immune response, including the anti-tumour immune response. Binding of the PD-1 ligands, PD-L1 and PD-L2, to the PD-1 receptor found on T cells, inhibits T cell proliferation, cytokine production, and cytotoxic activity. |
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Below package inserts are available for further reading:
| Document | Type | Information Source | |
|---|---|---|---|
| LOQTORZI Concentrate for solution for infusion | MPI, EU: SmPC | European Medicines Agency (EU) | |
| LOQTORZI Solution for injection | MPI, US: SPL/PLR | FDA, National Drug Code (US) |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
|---|---|---|
| L01FF13 | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01F Monoclonal antibodies and antibody drug conjugates → L01FF PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| LT | Valstybinė vaistų kontrolės tarnyba | 1101292 |
| US | FDA, National Drug Code | 70114-340, 83718-000 |
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