MACUGEN

This brand name is authorized in Lithuania, Romania, United States

Active ingredients

The drug MACUGEN contains one active pharmaceutical ingredient (API):

1 Pegaptanib UNII 3HP012Q0FH - PEGAPTANIB SODIUM

Pegaptanib is a pegylated modified oligonucleotide that binds with high specificity and affinity to extracellular Vascular Endothelial Growth Factor (VEGF165) inhibiting its activity. VEGF is a secreted protein that induces angiogenesis, vascular permeability and inflammation, all of which are thought to contribute to the progression of the neovascular (wet) form of AMD. Read about Pegaptanib

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
MACUGEN Solution for injection	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
S01LA03	Pegaptanib	S Sensory organs → S01 Ophthalmologicals → S01L Ocular vascular disorder agents → S01LA Antineovascularisation agents
Discover more medicines within S01LA03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1029679
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W64998001
Country: US	FDA, National Drug Code	Identifier(s): 68782-001