MADOPAR

This brand name is authorized in Austria, Australia, Germany, Estonia, Spain, Finland, Hong Kong, Croatia, Ireland, Italy, Japan, Lithuania, Malta, Mexico, Netherlands, New Zealand, Poland, Romania, Singapore, Turkey, United Kingdom, South Africa

Active ingredients

The drug MADOPAR contains a combination of these active pharmaceutical ingredients (APIs):

1 Levodopa UNII 46627O600J - LEVODOPA

According to the current understanding, the symptoms of Parkinson’s disease are related to depletion of dopamine in the corpus striatum. Dopamine does not cross the blood-brain barrier. Levodopa, the precursor of dopamine, crosses the blood brain barrier and relieves the symptoms of the disease. Read about Levodopa

2 Benserazide UNII B66E5RK36Q - BENSERAZIDE HYDROCHLORIDE

Benserazide (also called Serazide or Ro 4-4602) is a peripherally acting aromatic L-amino acid decarboxylase or DOPA decarboxylase inhibitor, which is unable to cross the blood–brain barrier. Read about Benserazide

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
MADOPAR Capsule, Rapid dispersible tablet	Medicines and Medical Devices Safety Authority (NZ)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
N04BA02	Levodopa and decarboxylase inhibitor	N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BA Dopa and dopa derivatives
Discover more medicines within N04BA02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 2225D, 2226E, 2227F, 2228G, 2229H, 2231K, 8218M, 8219N
Country: DE	Bundesinstitut für Arzneimittel und Medizinprodukte	Identifier(s): 00125440, 00125457, 00257905, 00257911, 00308956, 00326500, 00326552, 00326569, 01214192, 01351581, 01351612, 01364862, 01364879, 01393622, 01416027, 01602095, 02457212, 02457229, 02535113, 02535136, 03108407, 03108413, 03108436, 03146402, 03146419, 03395789, 03395803, 03501866, 03888606, 03888629, 04471392, 04611611, 04759756, 04759779, 04774796, 04775525, 04800252, 04800269, 04958697, 04958912, 05541976, 05960785, 06865215, 07309189, 07729394, 08699761, 08699784, 09194112, 09194141, 09396732, 12539313
Country: EE	Ravimiamet	Identifier(s): 1002014, 1077049, 1082911, 1082922, 1085161, 1149544, 1599611, 1599622
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 52146, 62162
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 032870, 032888, 372151, 526368
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 144773, 162060, 175693, 175799, 23992, 23999, 24003, 24012, 24019, 24025
Country: HK	Department of Health Drug Office	Identifier(s): 15442, 30945, 43315
Country: IE	Health Products Regulatory Authority	Identifier(s): 39748, 39756, 61646
Country: IT	Agenzia del Farmaco	Identifier(s): 023142033
Country: JP	医薬品医療機器総合機構	Identifier(s): 1169100F1079
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1001211, 1001213, 1001215, 1003373
Country: MT	Medicines Authority	Identifier(s): AA1343/01301, AA565/40302, AA565/40303, AA565/40304, AA729/00502, AA729/00503
Country: MX	Comisión Federal para la Protección contra Riesgos Sanitarios	Identifier(s): 82544
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 116971, 38563, 56677, 56685, 73695
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 1954, 1955, 1956, 1959, 1960
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100040373, 100040404, 100040410, 100040427, 100079040, 100079056, 100193800
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W51325001, W51325002, W58811002
Country: SG	Health Sciences Authority	Identifier(s): 05195P, 06119P, 06121P, 11075P
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699525094841, 8699525094858, 8699525150059, 8699525154828
Country: ZA	Health Products Regulatory Authority	Identifier(s): 31/5.4.1/0194, P/5.4.1/150