METVIX

This brand name is authorized in Austria, Brazil, Canada, Spain, Finland, Ireland, Malta, Netherlands, New Zealand, Singapore, United Kingdom, South Africa

Active ingredients

The drug METVIX contains one active pharmaceutical ingredient (API):

1 Methyl aminolevulinate
UNII 7S73606O1A - METHYL AMINOLEVULINATE HYDROCHLORIDE

Methyl aminolevulinate is a prodrug that is metabolized to protoporphyrin. After topical application of methyl aminolevulinate, porphyrins accumulate intracellularly in the treated skin lesions. The intracellular porphyrins (including PpIX) are photoactive, fluorescing compounds and, upon light activation in the presence of oxygen, singlet oxygen is formed which causes damage to cellular compartments, in particular the mitochondria. Light activation of accumulated porphyrins leads to a photochemical reaction and thereby phototoxicity to the light-exposed target cells.

Read about Methyl aminolevulinate

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
METVIX Cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
L01XD03 Methyl aminolevulinate L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XD Sensitizers used in photodynamic/radiation therapy
Discover more medicines within L01XD03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: BR Câmara de Regulação do Mercado de Medicamentos Identifier(s): 510101901177315
Country: CA Health Products and Food Branch Identifier(s): 02323273
Country: ES Centro de información online de medicamentos de la AEMPS Identifier(s): 64968
Country: FI Lääkealan turvallisuus- ja kehittämiskeskus Identifier(s): 085195
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 46502
Country: MT Medicines Authority Identifier(s): AA117/01402, AA117/01403
Country: NZ Medicines and Medical Devices Safety Authority Identifier(s): 10204
Country: SG Health Sciences Authority Identifier(s): 13410P
Country: ZA Health Products Regulatory Authority Identifier(s): A38/26/0528

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