REBIF

This brand name is authorized in Austria, Australia, Brazil, Canada, Cyprus, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Italy, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Tunisia, Turkey, United Kingdom, United States, South Africa

Active ingredients

The drug REBIF contains one active pharmaceutical ingredient (API):

1 Interferon beta-1a UNII XRO4566Q4R - INTERFERON BETA-1A

Interferon beta-1a exerts its biological effects by binding to specific receptors on the surface of human cells. This binding initiates a complex cascade of intracellular events that leads to the expression of numerous interferon-induced gene products and markers. Whether the mechanism of action of interferon beta-1a in MS is mediated by the same pathway as the biological effects described above is not known because the pathophysiology of MS is not well established. Read about Interferon beta-1a

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L03AB07	Interferon beta-1a	L Antineoplastic and immunomodulating agents → L03 Immunostimulants → L03A Immunostimulants → L03AB Interferons
Discover more medicines within L03AB07

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 8403G, 8968B, 9332E
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 525420401153414, 525420402151415
Country: CA	Health Products and Food Branch	Identifier(s): 02237319, 02237320, 02318253, 02318261
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 26.640-10-05
Country: EE	Ravimiamet	Identifier(s): 1010866, 1035931, 1071638, 1071683, 1117639, 1117640, 1226607, 1430660, 1430671, 1489147, 1489158, 1489169, 1489305, 1489316, 1489327, 1489338, 1489349, 1646704, 1646715, 1778508, 1778519
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 98063008, 98063009, 98063009IP
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 032660, 034977, 034988, 036108, 059873, 151341, 156713, 169894, 518977
Country: FR	Base de données publique des médicaments	Identifier(s): 62090595, 62332372, 62657978, 63866728, 66975533, 68319944, 68975699, 69483042
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 113916, 114131, 114155, 166030, 166033, 166369, 186508, 186511, 186516, 186518, 186524, 44036, 44068
Country: HK	Department of Health Drug Office	Identifier(s): 57955, 57957, 59718, 59719, 62254, 62255
Country: IE	Health Products Regulatory Authority	Identifier(s): 88291, 88292, 88367, 88368, 88369, 88556, 88834
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 6117, 6118
Country: IT	Agenzia del Farmaco	Identifier(s): 034091013, 034091025, 034091037, 034091049, 034091052, 034091064, 034091076, 034091088, 034091090, 034091102, 034091114, 034091126, 034091138, 034091140, 034091153, 034091165, 034091177, 034091203, 034091215
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1004423, 1005538, 1006944, 1006945, 1015559, 1015560, 1030645, 1036693, 1064264, 1071810, 1084982, 1084983, 1091260, 1091261, 1091262, 1091263, 1091264, 1091265, 1091266, 1091267, 1091268
Country: NL	Z-Index G-Standaard	Identifier(s): 14229897
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 100021, 100056, 100064, 100072, 100080, 100196
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 20695, 20696, 8897, 8898
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100085051, 100101666, 100159217, 100402439, 100402445
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W65162001, W65162002, W65162003, W65163001, W65163002, W65164001, W65164002, W65164003, W65165001
Country: SG	Health Sciences Authority	Identifier(s): 13974P, 13975P, 14524P, 14525P
Country: TN	Direction de la Pharmacie et du Médicament	Identifier(s): 22073031H, 22073032H, 22073033H, 22073034H, 6363054H, 6363055H
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699777950186, 8699777950209, 8699777950216, 8699777950353, 8699777950360, 8699777950377, 8699777950384
Country: US	FDA, National Drug Code	Identifier(s): 44087-0022, 44087-0044, 44087-3322, 44087-3344
Country: ZA	Health Products Regulatory Authority	Identifier(s): 34/34/0096, 35/34/0188, 45/34/1025, 45/34/1026