This brand name is authorized in United States
The drug RIVFLOZA contains one active pharmaceutical ingredient (API):
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1
Nedosiran
UNII 13U9R5J3WL - NEDOSIRAN
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Nedosiran is a double-stranded siRNA, conjugated to GalNAc aminosugar residues. After subcutaneous administration, the GalNAc-conjugated sugars bind to asialoglycoprotein receptors (ASGPR) to deliver nedosiran to hepatocytes. Nedosiran reduces levels of hepatic lactate dehydrogenase (LDH) via the degradation of LDHA messenger ribonucleic acid (mRNA) in hepatocytes through RNA interference. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| RIVFLOZA Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: US | FDA, National Drug Code | Identifier(s): 0169-5306, 0169-5307, 0169-5308 |
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