SIKLOS

This brand name is authorized in Austria, Cyprus, Estonia, Spain, Finland, France, Ireland, Lithuania, Netherlands, Poland, United Kingdom, United States

Active ingredients

The drug SIKLOS contains one active pharmaceutical ingredient (API):

1 Hydroxycarbamide
UNII X6Q56QN5QC - HYDROXYUREA

One of the mechanisms by which hydroxycarbamide acts is the elevation of foetal haemoglobin (HbF) concentrations in sickle cell patients. In addition hydroxycarbamide causes an immediate inhibition of DNA synthesis by acting as a ribonucleotide reductase inhibitor, without interfering with the synthesis of ribonucleic acid or protein.

Read about Hydroxycarbamide

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
SIKLOS Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
L01XX05 Hydroxycarbamide L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents
Discover more medicines within L01XX05

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: EE Ravimiamet Identifier(s): 1304558, 1521009, 1521010, 1521021
Country: ES Centro de información online de medicamentos de la AEMPS Identifier(s): 07397001, 07397002
Country: FI Lääkealan turvallisuus- ja kehittämiskeskus Identifier(s): 162865, 371181
Country: FR Base de données publique des médicaments Identifier(s): 66384911, 66898948
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 139565, 193138
Country: LT Valstybinė vaistų kontrolės tarnyba Identifier(s): 1030739, 1059505, 1059506, 1059507
Country: NL Z-Index G-Standaard, PRK Identifier(s): 85855, 96911
Country: PL Rejestru Produktów Leczniczych Identifier(s): 100033054, 100316585
Country: US FDA, National Drug Code Identifier(s): 71770-100, 71770-105, 71770-120

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