SIKLOS

This brand name is authorized in United States. It is also authorized in Austria, Croatia, Cyprus, Estonia, Finland, France, Ireland, Italy, Lithuania, Netherlands, Poland, Spain, UK.

Active ingredients

The drug SIKLOS contains one active pharmaceutical ingredient (API):

1	Hydroxycarbamide UNII X6Q56QN5QC - HYDROXYUREA
	One of the mechanisms by which hydroxycarbamide acts is the elevation of foetal haemoglobin (HbF) concentrations in sickle cell patients. In addition hydroxycarbamide causes an immediate inhibition of DNA synthesis by acting as a ribonucleotide reductase inhibitor, without interfering with the synthesis of ribonucleic acid or protein.
	Read more about Hydroxycarbamide

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
SIKLOS Film-coated tablet	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L01XX05	Hydroxycarbamide	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents
Discover more medicines within L01XX05

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
EE	Ravimiamet	1304558, 1521009, 1521010, 1521021
ES	Centro de información online de medicamentos de la AEMPS	07397001, 07397002
FI	Lääkealan turvallisuus- ja kehittämiskeskus	162865, 371181
FR	Base de données publique des médicaments	66384911, 66898948
GB	Medicines & Healthcare Products Regulatory Agency	139565, 193138
IT	Agenzia del Farmaco	045338011, 045338023, 045338035, 045338047
LT	Valstybinė vaistų kontrolės tarnyba	1030739, 1059505, 1059506, 1059507
NL	Z-Index G-Standaard, PRK	85855, 96911
PL	Rejestru Produktów Leczniczych	100033054, 100316585
US	FDA, National Drug Code	71770-100, 71770-105, 71770-120