SYLVANT

This brand name is authorized in Austria, Brazil, Canada, Cyprus, Estonia, Spain, Finland, France, Hong Kong, Ireland, Israel, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Turkey, United Kingdom, United States

Active ingredients

The drug SYLVANT contains one active pharmaceutical ingredient (API):

1 Siltuximab
UNII T4H8FMA7IM - SILTUXIMAB

Siltuximab is a monoclonal antibody that forms high affinity, stable complexes with soluble bioactive forms of human IL-6. Siltuximab prevents the binding of human IL-6 to both soluble and membrane-bound IL-6 receptors (IL-6R), thus inhibiting the formation of the hexameric signaling complex with gp130 on the cell surface.

Read about Siltuximab

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
SYLVANT Powder for concentrate for solution for infusion European Medicines Agency (EU) MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
L04AC11 L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AC Interleukin inhibitors
Discover more medicines within L04AC11

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: BR Câmara de Regulação do Mercado de Medicamentos Identifier(s): 514515080027701, 514515080027801
Country: CA Health Products and Food Branch Identifier(s): 02435128, 02435136
Country: EE Ravimiamet Identifier(s): 1649189, 1649190
Country: ES Centro de información online de medicamentos de la AEMPS Identifier(s): 114928001
Country: FI Lääkealan turvallisuus- ja kehittämiskeskus Identifier(s): 161783
Country: FR Base de données publique des médicaments Identifier(s): 60622302, 63846800
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 247966, 247977
Country: HK Department of Health Drug Office Identifier(s): 64495, 64496
Country: IL מִשְׂרַד הַבְּרִיאוּת Identifier(s): 7796, 7797
Country: LT Valstybinė vaistų kontrolės tarnyba Identifier(s): 1073468, 1073469
Country: NL Z-Index G-Standaard, PRK Identifier(s): 117099, 117102
Country: NZ Medicines and Medical Devices Safety Authority Identifier(s): 17150, 17151
Country: PL Rejestru Produktów Leczniczych Identifier(s): 100317716, 100317722
Country: RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale Identifier(s): W66521001, W66522001
Country: SG Health Sciences Authority Identifier(s): 14762P, 14763P
Country: TR İlaç ve Tıbbi Cihaz Kurumu Identifier(s): 8680885579178, 8680885579185
Country: US FDA, National Drug Code Identifier(s): 57894-420, 57894-421, 73090-420, 73090-421

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