SYLVANT

This brand name is authorized in United States. It is also authorized in Austria, Brazil, Canada, Croatia, Cyprus, Estonia, Finland, France, Hong Kong SAR China, Ireland, Israel, Italy, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Spain, Turkey, UK.

Active ingredients

The drug SYLVANT contains one active pharmaceutical ingredient (API):

1	Siltuximab UNII T4H8FMA7IM - SILTUXIMAB
	Siltuximab is a monoclonal antibody that forms high affinity, stable complexes with soluble bioactive forms of human IL-6. Siltuximab prevents the binding of human IL-6 to both soluble and membrane-bound IL-6 receptors (IL-6R), thus inhibiting the formation of the hexameric signaling complex with gp130 on the cell surface.
	Read more about Siltuximab

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
SYLVANT Powder for concentrate for solution for infusion	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L04AC11		L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AC Interleukin inhibitors
Discover more medicines within L04AC11

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
BR	Câmara de Regulação do Mercado de Medicamentos	514515080027701, 514515080027801
CA	Health Products and Food Branch	02435128, 02435136
EE	Ravimiamet	1649189, 1649190
ES	Centro de información online de medicamentos de la AEMPS	114928001
FI	Lääkealan turvallisuus- ja kehittämiskeskus	161783
FR	Base de données publique des médicaments	60622302, 63846800
GB	Medicines & Healthcare Products Regulatory Agency	247966, 247977
HK	Department of Health Drug Office	64495, 64496
IL	מִשְׂרַד הַבְּרִיאוּת	7796, 7797
IT	Agenzia del Farmaco	043447010, 043447022
LT	Valstybinė vaistų kontrolės tarnyba	1073468, 1073469
NL	Z-Index G-Standaard, PRK	117099, 117102
NZ	Medicines and Medical Devices Safety Authority	17150, 17151
PL	Rejestru Produktów Leczniczych	100317716, 100317722
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W66521001, W66522001
SG	Health Sciences Authority	14762P, 14763P
TR	İlaç ve Tıbbi Cihaz Kurumu	8680885579178, 8680885579185
US	FDA, National Drug Code	57894-420, 57894-421, 73090-420, 73090-421