This brand name is authorized in United States
The drug TEMODAR contains one active pharmaceutical ingredient (API):
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1
Temozolomide
UNII YF1K15M17Y - TEMOZOLOMIDE
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Temozolomide is a triazene, which undergoes rapid chemical conversion at physiologic pH to the active monomethyl triazenoimidazole carboxamide (MTIC). The cytotoxicity of MTIC is thought to be due primarily to alkylation at the O6 position of guanine with additional alkylation also occurring at the N7 position. Cytotoxic lesions that develop subsequently are thought to involve aberrant repair of the methyl adduct. |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: US | FDA, National Drug Code | Identifier(s): 0085-1366, 0085-1381, 0085-1417, 0085-1425, 0085-1430, 0085-1519, 0085-3004 |
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