TEZSPIRE

This brand name is authorized in Austria, Canada, Estonia, Spain, France, Croatia, Ireland, Israel, Italy, Japan, Lithuania, Romania, United Kingdom, United States

Active ingredients

The drug TEZSPIRE contains one active pharmaceutical ingredient (API):

1 Tezepelumab UNII RJ1IW3B4QX - TEZEPELUMAB

Tezepelumab is a monoclonal antibody (IgG2λ) directed against thymic stromal lymphopoietin (TSLP), preventing its interaction with the heterodimeric TSLP receptor. In asthma, both allergic and non-allergic triggers induce TSLP production. Blocking TSLP with tezepelumab reduces a broad spectrum of biomarkers and cytokines associated with airway inflammation; however, the mechanism of action of tezepelumab in asthma has not been definitively established. Read about Tezepelumab

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
TEZSPIRE Solution for injection	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
R03DX11		R Respiratory system → R03 Drugs for obstructive airway diseases → R03D Other systemic drugs for obstructive airway diseases → R03DX Other systemic drugs for obstructive airway diseases
Discover more medicines within R03DX11

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: CA	Health Products and Food Branch	Identifier(s): 02529548, 02529556
Country: EE	Ravimiamet	Identifier(s): 1889949, 3053528, 3053539, 3053540
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 1221677001, 1221677003
Country: FR	Base de données publique des médicaments	Identifier(s): 68954908, 69714595
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 9255
Country: IT	Agenzia del Farmaco	Identifier(s): 050354012, 050354024, 050354036, 050354048
Country: JP	医薬品医療機器総合機構	Identifier(s): 2290403G1025
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1095625, 1095953, 1096532, 1097001
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W69162001, W69476001
Country: US	FDA, National Drug Code	Identifier(s): 55513-100, 55513-112