TRIJARDY XR

This brand name is authorized in United States

Active ingredients

The drug TRIJARDY XR contains a combination of these active pharmaceutical ingredients (APIs):

1 Empagliflozin UNII HDC1R2M35U - EMPAGLIFLOZIN
Empagliflozin is a reversible, highly potent (IC₅₀ of 1.3 nmol) and selective competitive inhibitor of sodium-glucose co-transporter 2 (SGLT2). Empagliflozin improves glycaemic control in patients with type 2 diabetes by reducing renal glucose reabsorption. Read about Empagliflozin
2 Linagliptin UNII 3X29ZEJ4R2 - LINAGLIPTIN
Linagliptin is an inhibitor of the enzyme DPP-4 (dipeptidyl peptidase 4, EC 3.4.14.5) an enzyme which is involved in the inactivation of the incretin hormones GLP-1 and GIP (glucagon-like peptide1, glucose-dependent insulinotropic polypeptide). These hormones are rapidly degraded by the enzyme DPP-4. Both incretin hormones are involved in the physiological regulation of glucose homeostasis. Read about Linagliptin
3 Metformin UNII 786Z46389E - METFORMIN HYDROCHLORIDE
Metformin is a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycaemia. Read about Metformin

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
TRIJARDY XR Extended-release tablet	FDA, National Drug Code (US)	MPI, US: SPL/PLR

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: US	FDA, National Drug Code	Identifier(s): 0597-0380, 0597-0385, 0597-0390, 0597-0395

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