TYKERB

This brand name is authorized in Australia, Brazil, Canada, Hong Kong, Israel, Japan, Mexico, New Zealand, Singapore, Turkey, United States, South Africa

Active ingredients

The drug TYKERB contains one active pharmaceutical ingredient (API):

1 Lapatinib
UNII G873GX646R - LAPATINIB DITOSYLATE

Lapatinib, a 4-anilinoquinazoline, is an inhibitor of the intracellular tyrosine kinase domains of both EGFR (ErbB1) and of HER2 (ErbB2) receptors (estimated Kiapp values of 3nM and 13nM, respectively) with a slow off-rate from these receptors (half-life greater than or equal to 300 minutes). Lapatinib inhibits ErbB-driven tumour cell growth in vitro and in various animal models.

Read about Lapatinib

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
TYKERB Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
L01EH01 Lapatinib L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors
Discover more medicines within L01EH01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: AU Pharmaceutical Benefits Scheme Identifier(s): 11251E, 9148L
Country: BR Câmara de Regulação do Mercado de Medicamentos Identifier(s): 526517060090017
Country: CA Health Products and Food Branch Identifier(s): 02326442
Country: HK Department of Health Drug Office Identifier(s): 56194
Country: IL מִשְׂרַד הַבְּרִיאוּת Identifier(s): 6192
Country: JP 医薬品医療機器総合機構 Identifier(s): 4291022F1026
Country: MX Comisión Federal para la Protección contra Riesgos Sanitarios Identifier(s): 417M2008
Country: NZ Medicines and Medical Devices Safety Authority Identifier(s): 13000
Country: SG Health Sciences Authority Identifier(s): 13366P
Country: TR İlaç ve Tıbbi Cihaz Kurumu Identifier(s): 8699504092127
Country: US FDA, National Drug Code Identifier(s): 0078-0671
Country: ZA Health Products Regulatory Authority Identifier(s): 42/26/0275

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