VEKLURY

This brand name is authorized in Austria, Brazil, Canada, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Ireland, Israel, Italy, Japan, Lithuania, Netherlands, Poland, Romania, United Kingdom, United States, South Africa

Active ingredients

The drug VEKLURY contains one active pharmaceutical ingredient (API):

1 Remdesivir UNII 3QKI37EEHE - REMDESIVIR

Remdesivir is an adenosine nucleotide prodrug that is metabolized within host cells to form the pharmacologically active nucleoside triphosphate metabolite. Remdesivir triphosphate acts as an analog of adenosine triphosphate (ATP) and competes with the natural ATP substrate for incorporation into nascent RNA chains by the SARS-CoV-2 RNA-dependent RNA polymerase, which results in delayed chain termination during replication of the viral RNA. As an additional mechanism, remdesivir triphosphate can also inhibit viral RNA synthesis following its incorporation into the template viral RNA as a result of read-through by the viral polymerase that may occur in the presence of higher nucleotide concentrations. Read about Remdesivir

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
VEKLURY Powder for concentrate for solution for infusion	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
J05AB16		J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
Discover more medicines within J05AB16

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 546821040001101
Country: CA	Health Products and Food Branch	Identifier(s): 02502143
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 6608-MEE-0921
Country: EE	Ravimiamet	Identifier(s): 1821822, 1822115
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 1201459002
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 542115
Country: FR	Base de données publique des médicaments	Identifier(s): 69284439
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 387373, 387471
Country: HK	Department of Health Drug Office	Identifier(s): 66766
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 8891
Country: IT	Agenzia del Farmaco	Identifier(s): 048854018, 048854020
Country: JP	医薬品医療機器総合機構	Identifier(s): 6250407D1020
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1090741, 1090742
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100437716, 100437722
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W67196001, W67197001
Country: US	FDA, National Drug Code	Identifier(s): 61958-2901, 61958-2902
Country: ZA	Health Products Regulatory Authority	Identifier(s): 55/20.2.8/0458