VENCLYXTO

This brand name is authorized in Austria, Cyprus, Estonia, Spain, Finland, France, Croatia, Ireland, Italy, Lithuania, Netherlands, Poland, Romania, Tunisia, Turkey, United Kingdom

Active ingredients

The drug VENCLYXTO contains one active pharmaceutical ingredient (API):

1 Venetoclax UNII N54AIC43PW - VENETOCLAX

Venetoclax is a potent, selective inhibitor of B-cell lymphoma (BCL)-2, an anti-apoptotic protein. Overexpression of BCL-2 has been demonstrated in CLL cells where it mediates tumour cell survival and has been associated with resistance to chemotherapeutics. Venetoclax binds directly to the BH3-binding groove of BCL-2, displacing BH3 motif-containing pro-apoptotic proteins like BIM, to initiate mitochondrial outer membrane permeabilization (MOMP), caspase activation, and programmed cell death. Read about Venetoclax

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
VENCLYXTO Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01XX52		L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents
Discover more medicines within L01XX52

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: EE	Ravimiamet	Identifier(s): 1734386, 1734397, 1734409, 1734410, 1734421, 1734432, 1734443
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 161138002, 161138004, 161138005
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 104541, 108133, 137028, 599982
Country: FR	Base de données publique des médicaments	Identifier(s): 62598280, 63696471, 64449755
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 337594, 337595, 337596, 337598, 337600
Country: IE	Health Products Regulatory Authority	Identifier(s): 88970, 88971, 88972, 88973, 88974
Country: IT	Agenzia del Farmaco	Identifier(s): 045198013, 045198025, 045198037, 045198049, 045198052, 045198064, 045198076
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1081759, 1081760, 1081761, 1081762, 1081763, 1081764, 1081765
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 138231, 138258, 138266
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100381861, 100381878, 100381884
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W64703001, W64704001, W64705001, W64705002, W64705003
Country: TN	Direction de la Pharmacie et du Médicament	Identifier(s): 16913041H, 16913042H, 16913043H, 16913044H, 1691345H
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8680656080438, 8680656080445, 8680656080452, 8680656080469, 8680656080476, 8680656080483, 8680656080490