VUMERITY

This brand name is authorized in Austria, Estonia, Spain, Finland, France, Croatia, Ireland, Israel, Italy, Lithuania, Poland, Romania, United States

Active ingredients

The drug VUMERITY contains one active pharmaceutical ingredient (API):

1 Diroximel fumarate UNII K0N0Z40J3W - DIROXIMEL FUMARATE

Diroximel fumarate is indicated for the treatment of relapsing forms of multiple sclerosis (MS). The mechanism by which diroximel fumarate exerts therapeutic effects in MS is not fully understood. Diroximel fumarate acts via the major active metabolite, monomethyl fumarate. Preclinical studies indicate that the pharmacodynamic responses of monomethyl fumarate appears to be mediated, at least in part, through activation of the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) transcriptional pathway. Read about Diroximel fumarate

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
VUMERITY Delayed-release capsule	FDA, National Drug Code (US)	MPI, US: SPL/PLR
VUMERITY Gastro-resistant hard capsule	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L04AX09		L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AX Other immunosuppressants
Discover more medicines within L04AX09

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: EE	Ravimiamet	Identifier(s): 1866607, 1866618
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 1211585001
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 543763
Country: FR	Base de données publique des médicaments	Identifier(s): 67170230
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 8796
Country: IT	Agenzia del Farmaco	Identifier(s): 049807011, 049807023
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1093690, 1093691
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100462149
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W68381001, W68381002
Country: US	FDA, National Drug Code	Identifier(s): 64406-020