VYTORIN

This brand name is authorized in Australia, Brazil, Germany, Ecuador, Spain, Hong Kong, Italy, Mexico, Singapore, United States

Active ingredients

The drug VYTORIN contains a combination of these active pharmaceutical ingredients (APIs):

1 Ezetimibe UNII EOR26LQQ24 - EZETIMIBE

Ezetimibe is in a new class of lipid-lowering compounds that selectively inhibit the intestinal absorption of cholesterol. The molecular target of ezetimibe is the sterol transporter, Niemann-Pick C1-Like 1 (NPC1L1), which is responsible for the intestinal uptake of cholesterol. Read about Ezetimibe

2 Simvastatin UNII AGG2FN16EV - SIMVASTATIN

Simvastatin has a potent activity in inhibiting HMG-CoA reductase (3-hydroxy–3-ethylglutaryl-CoA-reductase). Simvastatin has been shown to reduce both normal and elevated LDL-C concentrations. Read about Simvastatin

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
VYTORIN Tablet	FDA, National Drug Code (US)	MPI, US: SPL/PLR

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
C10BA02	Simvastatin and ezetimibe	C Cardiovascular system → C10 Lipid modifying agents → C10B Lipid modifying agents, combinations → C10BA Combinations of various lipid modifying agents
Discover more medicines within C10BA02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 8881K, 8882L, 9483D, 9484E
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 525503402114214, 525503403110212, 525503404117210, 525503405113219, 525503406111211, 525503407116215, 525516020019403, 525516020019503, 525516020019603
Country: DE	Bundesinstitut für Arzneimittel und Medizinprodukte	Identifier(s): 15293338, 17309718
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 25.819-08-04, 25.820-08-04, 25.822-08-04
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 66571, PA1286-062-002, PA1286-062-003
Country: HK	Department of Health Drug Office	Identifier(s): 53014, 53016, 53017
Country: IT	Agenzia del Farmaco	Identifier(s): 036690067, 036690218, 036690360
Country: MX	Comisión Federal para la Protección contra Riesgos Sanitarios	Identifier(s): 127M2004
Country: SG	Health Sciences Authority	Identifier(s): 13011P, 13012P
Country: US	FDA, National Drug Code	Identifier(s): 55289-280, 55289-520, 66582-311, 66582-312, 66582-313, 66582-315