YESCARTA

This brand name is authorized in Austria, Canada, Estonia, Spain, Finland, France, Ireland, Israel, Lithuania, Poland, United Kingdom

Active ingredients

The drug YESCARTA contains one active pharmaceutical ingredient (API):

1 Axicabtagene ciloleucel
UNII U2I8T43Y7R - AXICABTAGENE CILOLEUCEL

Axicabtagene ciloleucel, an engineered autologous T-cell immunotherapy product, binds to CD19 expressing cancer cells and normal B cells. Following anti-CD19 CAR T-cell engagement with CD19 expressing target cells, a sequence of events leads to apoptosis and necrosis of CD19-expressing target cells. Αxicabtagene ciloleucel is indicated for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) and primary mediastinal large B-cell lymphoma (PMBCL), after two or more lines of systemic therapy.

Read about Axicabtagene ciloleucel

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
YESCARTA Dispersion for infusion European Medicines Agency (EU) MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
L01X Other antineoplastic agents L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents
Discover more medicines within L01X
L01XL03 L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XL Antineoplastic cell and gene therapy
Discover more medicines within L01XL03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: CA Health Products and Food Branch Identifier(s): 02485648
Country: EE Ravimiamet Identifier(s): 1778597
Country: ES Centro de información online de medicamentos de la AEMPS Identifier(s): 1181299001
Country: FI Lääkealan turvallisuus- ja kehittämiskeskus Identifier(s): 402302
Country: FR Base de données publique des médicaments Identifier(s): 63887327
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 364610
Country: IL מִשְׂרַד הַבְּרִיאוּת Identifier(s): 8696
Country: LT Valstybinė vaistų kontrolės tarnyba Identifier(s): 1086198
Country: PL Rejestru Produktów Leczniczych Identifier(s): 100410634

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