ZIRABEV

This brand name is authorized in Austria, Canada, Estonia, Spain, France, Ireland, Lithuania, Netherlands, New Zealand, Poland, Romania, Turkey, United Kingdom, United States

Active ingredients

The drug ZIRABEV contains one active pharmaceutical ingredient (API):

1 Bevacizumab
UNII 2S9ZZM9Q9V - BEVACIZUMAB

Bevacizumab binds to vascular endothelial growth factor (VEGF), the key driver of vasculogenesis and angiogenesis, and thereby inhibits the binding of VEGF to its receptors, Flt-1 (VEGFR-1) and KDR (VEGFR-2), on the surface of endothelial cells. Neutralising the biological activity of VEGF regresses the vascularisation of tumours, normalises remaining tumour vasculature, and inhibits the formation of new tumour vasculature, thereby inhibiting tumour growth.

Read about Bevacizumab

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
L01FG01 Bevacizumab L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01F Monoclonal antibodies and antibody drug conjugates → L01FG VEGF/VEGFR (Vascular Endothelial Growth Factor) inhibitors
Discover more medicines within L01FG01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: CA Health Products and Food Branch Identifier(s): 02489430, 02489449
Country: EE Ravimiamet Identifier(s): 1789432, 1789443
Country: ES Centro de información online de medicamentos de la AEMPS Identifier(s): 1181344001, 1181344002
Country: FR Base de données publique des médicaments Identifier(s): 64224872
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 384843, 384855
Country: LT Valstybinė vaistų kontrolės tarnyba Identifier(s): 1087076, 1087077
Country: NL Z-Index G-Standaard, PRK Identifier(s): 76910, 76929
Country: NZ Medicines and Medical Devices Safety Authority Identifier(s): 21604
Country: PL Rejestru Produktów Leczniczych Identifier(s): 100416884
Country: RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale Identifier(s): W66686001, W66686002
Country: TR İlaç ve Tıbbi Cihaz Kurumu Identifier(s): 8681308771087, 8681308771094
Country: US FDA, National Drug Code Identifier(s): 0069-0315, 0069-0342

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