This brand name is authorized in Austria, Estonia, Croatia, Ireland, Italy, Lithuania, Poland, United States
The drug ZYNRELEF contains a combination of these active pharmaceutical ingredients (APIs):
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1
Bupivacaine
UNII Y8335394RO - BUPIVACAINE
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Bupivacaine is an amide-type, long-acting local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation. |
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2
Meloxicam
UNII VG2QF83CGL - MELOXICAM
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Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam family, with anti-inflammatory, analgesic and antipyretic properties. The anti-inflammatory activity of meloxicam has been proven in classical models of inflammation. As with other NSAID, its precise mechanism of action remains unknown. However, there is at least one common mode of action shared by all NSAID (including meloxicam): inhibition of the biosynthesis of prostaglandins, known inflammation mediators. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N01BB59 | N Nervous system → N01 Anesthetics → N01B Anesthetics, local → N01BB Amides | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1828739, 1828818, 1828829 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 049057019, 049057021, 049057033 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1091247, 1091248, 1091249 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100441920, 100441936, 100441942 |
| Country: US | FDA, National Drug Code | Identifier(s): 47426-301, 47426-302, 47426-303, 47426-304 |
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