Specific codes in ICD-10 are unique alphanumeric designations used to identify and categorize diseases, disorders, and conditions. They consist of 3-5 characters, including both letters and numbers, that provide a high level of detail and specificity.
| Language | Translation |
|---|---|
|
|
Distal interphalangeal psoriatic arthropathy |
|
|
Arthropathie psoriasique distale interphalangienne (L40.5) |
| Level | Code | Title | |
|---|---|---|---|
| 1 | XIII | Diseases of the musculoskeletal system and connective tissue | |
| 2 | M05-M14 | Inflammatory polyarthropathies | |
| 3 | M07 | Psoriatic and enteropathic arthropathies | |
| 4 | M07.0 | Distal interphalangeal psoriatic arthropathy |
| Active Ingredient |
|---|
|
Tofacitinib is a potent, selective inhibitor of the JAK family. In human cells, tofacitinib preferentially inhibits signalling by heterodimeric cytokine receptors that associate with JAK3 and/or JAK1. Inhibition of JAK1 and JAK3 by tofacitinib attenuates signalling of interleukins and type I and type II interferons, which will result in modulation of the immune and inflammatory response. |
|
Ustekinumab is a fully human IgG1κ monoclonal antibody that binds with specificity to the shared p40 protein subunit of human cytokines interleukin (IL)-12 and IL-23. Ustekinumab inhibits the bioactivity of human IL-12 and IL-23 by preventing p40 from binding to the IL-12R1 receptor protein expressed on the surface of immune cells. Abnormal regulation of IL 12 and IL 23 has been associated with immune mediated diseases, such as psoriasis, psoriatic arthritis, Crohn's disease and ulcerative colitis. |