Carcinoma of the prostate, especially in cases unresponsive to, or relapsing after, treatment by conventional oestrogens (stilboestrol, polyoestradiol phosphate etc.) or by orchidectomy.
For this indication, competent medicine agencies globally authorize below treatments:
140 - 1,400 mg
From 46.667 To 466.667 mg 3 time(s) per day every day
Dosage range may be from 140 to 1,400 mg a day by mouth. The capsules should be taken not less than 1 hour before or 2 hours after meals. Milk, milk products or drugs containing calcium, magnesium or aluminium (e.g. antacids) must not be taken simultaneously with estramustine. Standard starting dosage is 560-840 mg a day in divided doses with later adjustment according to response and gastrointestinal tolerance.
It should be taken not less than 1 hour before or 2 hours after meals.