Active Ingredient: Letrozole
For this indication, competent medicine agencies globally authorize below treatments:
Oral
2.5 - 2.5 mg
From 2.5 To 2.5 mg once every day
The recommended dose of Letrozole is 2.5 mg once daily. No dose adjustment is required for elderly patients.
In patients with advanced or metastatic breast cancer, treatment with letrozole should continue until tumour progression is evident.
In the adjuvant and extended adjuvant setting, treatment with letrozole should continue for 5 years or until tumour relapse occurs, whichever is first.
In the adjuvant setting a sequential treatment schedule (letrozole 2 years followed by tamoxifen 3 years) could also be considered. In the neoadjuvant setting, treatment with letrozole could be continued for 4 to 8 months in order to establish optimal tumour reduction. If the response is not adequate, treatment with letrozole should be discontinued and surgery scheduled and/or further treatment options discussed with the patient.
Can be taken with or without food.
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