Gastric cancer

Active Ingredient: Epirubicin

Indication for Epirubicin

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

50-90 mg/m² once every 3 weeks

Route of admnistration


Defined daily dose

50 - 90 mg per m² of body surface area (BSA)

Dosage regimen

From 50 To 90 mg per m² of body surface area (BSA) once every 21 day(s)

Detailed description

The following doses of epirubicin are commonly used in monotherapy and combination chemotherapy, as shown:

 Epirubicin Dose (mg/m²)a
Cancer IndicationMonotherapyCombination Therapy
Gastric cancer60–9050

a Doses generally given Day 1 or Day 1, 2 and 3 at 21-day intervals

Dosage considerations

For high dose treatment, epirubicin may be given as an intravenous bolus over 3-5 minutes or as an infusion of up to 30 minutes duration.

Active ingredient


Epirubicin is a cytotoxic active antibiotic from the anthracycline group. The mechanism of action of epirubicin is related to its ability to bind to DNA. Cell culture studies have shown rapid cell penetration, localisation in the nucleus and inhibition of nucleic acid synthesis and mitosis.

Read more about Epirubicin

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