Coronavirus disease 2019 (COVID-19) who do not require oxygen supplementation

Active Ingredient: Sotrovimab

Indication for Sotrovimab

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Sotrovimab is indicated for the treatment of adults and adolescents (aged 12 years and over and weighing at least 40 kg) with coronavirus disease 2019 (COVID-19) who do not require oxygen supplementation and who are at increased risk of progressing to severe COVID-19.

For this indication, competent medicine agencies globally authorize below treatments:

500 mg once

Route of admnistration


Defined daily dose

500 - 500 mg

Dosage regimen

From 500 To 500 mg once every day

Detailed description

The recommended dose is a single 500 mg intravenous infusion administered following dilution.

Dosage considerations

Prime the infusion set and administer as a single IV infusion for 30 minutes at room temperature.

Treatment must not be administered as an intravenous push or bolus.

Active ingredient


Sotrovimab is a dual action, engineered human IgG1 mAb that binds to a conserved epitope on the spike protein receptor binding domain of SARS-CoV-2. It is used for the treatment of symptomatic adults and adolescents with acute covid-19 infection who do not require oxygen supplementation and who are at increased risk of progressing to severe covid infection.

Read more about Sotrovimab

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