Magnetic resonance imaging of liver with contrast

Indication for Gadobenic acid

Population group: Suitable for both men and women, only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Gadobenic acid is a paramagnetic contrast agent for use in diagnostic magnetic resonance imaging (MRI) of the liver in adults and children (above the age of 2 years).

Gadobenic acid should be used only when diagnostic information is essential and not available with unenhanced magnetic resonance imaging (MRI) and when delayed phase imaging is required.

For this indication, competent medicine agencies globally authorize below treatments:

0.05 mmol/kg

Route of admnistration


Defined daily dose

0.05 - 0.05 mmol per kg of body weight

Dosage regimen

From 0.05 To 0.05 mmol per kg of body weight once every day

Detailed description

The recommended dose of gadobenic acid in adult patients and children is 0.05 mmol/kg body weight (0.1 mL/kg of the 0.5 M solution). The lowest dose that provides sufficient enhancement for diagnostic purposes should be used. The dose should be calculated based on the patient’s body weight, and should not exceed the recommended dose per kilogram of body weight detailed in this section.

If required, the injection can be repeated in subjects with normal kidney function.

Dosage considerations

The product should be administered intravenously either as a bolus or slow injection (10 mL/min.), see table for post-contrast imaging acquisition.

The injection should be followed by a flush of sodium chloride 9 mg/ml (0.9%) solution for injection.

Post-contrast imaging acquisition:

LiverDynamic imaging: Immediately following bolus injection.
Delayed imaging: between 40 and 120 minutes following the injection, depending on the individual imaging needs.

Active ingredient

Gadobenic acid is a paramagnetic contrast agent for use in diagnostic magnetic resonance imaging (MRI) of the liver.

Read more about Gadobenic acid

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