Prevention of uptake of radioactive iodine in the thyroid after nuclear accidents

Active Ingredient: Potassium iodide

Indication for Potassium iodide

Population group: only minors (0 - 18 years old) , adults (18 years old or older)
Therapeutic intent: Preventive action

For use after nuclear accidents with release of radioactive iodine isotopes to prevent the uptake of radioactive iodine in the thyroid after intake or inhalation of this substance.

For this indication, competent medicine agencies globally authorize below treatments:

100 mg once

For:

Dosage regimens

Oral, 100 milligrams potassium iodide, one dose.

Detailed description

100 mg iodine.

Duration of administration

A single administration is usually sufficient.

If the release of radioactive iodine continues (>24 hours), with repeated exposure, intake of contaminated food or drinking water and if evacuation is not possible, a repeated administration may be necessary.

Older adults (>60 years) should not receive more than one dose. They are at higher risk of adverse health effects if they receive repeated doses of stable iodine.

Adults above 40 years of age

The intake of iodine tablets is not recommended for persons above 40 years because they are less likely to benefit from treatment with iodine tablets after exposure to radioactive iodine.

For children 3-12 years old 50 mg once and for children 1 month to 3 years old 25 mg once

For:

Dosage regimens

Regimen A: In case that patient age in years is ≥ 3 and patient age in years is ≤ 12, oral, 50 milligrams potassium iodide, one dose.

Regimen B: In case that patient age in years is ≤ 3, oral, 25 milligrams potassium iodide, one dose.

Detailed description

Children from 3 to 12 years: 50 mg iodine.

Children from 1 month to 3 years: 25 mg iodine.

Duration of administration

A single administration is usually sufficient.

If the release of radioactive iodine continues (>24 hours), with repeated exposure, intake of contaminated food or drinking water and if evacuation is not possible, a repeated administration may be necessary.

12.5 mg once for newborns younger than a month

For:

Dosage regimens

Oral, 12.5 milligrams potassium iodide, one dose.

Detailed description

Newborns and babies younger than a month: 12.5 mg iodine.

Neonates should not receive more than one dose.

Active ingredient

Potassium iodide

Potassium iodide is indicated as a thyroid-blocking agent to prevent the uptake of radioactive iodine, for example after a nuclear accident or during a nuclear medicine investigation before administering a radioiodinated compound, which is metabolised to iodide or which contains radioiodine impurities.

Read more about Potassium iodide

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