Invasive candidiasis

Active Ingredient: Micafungin

Indication for Micafungin

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Treatment of invasive candidiasis.

For this indication, competent medicine agencies globally authorize below treatments:

100 mg once daily

Route of admnistration


Defined daily dose

100 - 100 mg

Dosage regimen

From 100 To 100 mg once every day

Detailed description

Specimens for fungal culture and other relevant laboratory studies (including histopathology) should be obtained prior to therapy to isolate and identify causative organism(s). Therapy may be instituted before the results of the cultures and other laboratory studies are known. However, once these results become available, antifungal therapy should be adjusted accordingly.

The dose regimen of micafungin depends on the body weight of the patient as given in the following table.

Use in adults, adolescents ≥16 years of age and elderly:

IndicationBody weight >40 kgBody weight ≤40 kg
Treatment of invasive candidiasis100 mg/day*2 mg/kg/day*

* If the patient’s response is inadequate, e.g. persistence of cultures or if clinical condition does not improve, the dose may be increased to 200 mg/day in patients weighing >40 kg or 4 mg/kg/day in patients ≤40 kg.

Treatment duration

The treatment duration of Candida infection should be a minimum of 14 days. The antifungal treatment should continue for at least one week after two sequential negative blood cultures have been obtained and after resolution of clinical signs and symptoms of infection.

Dosage considerations

After reconstitution and dilution, the solution should be administered by intravenous infusion over approximately 1 hour.

Active ingredient


Micafungin non-competitively inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall. 1,3-β-D-glucan is not present in mammalian cells. Micafungin exhibits fungicidal activity against most Candida species and prominently inhibits actively growing hyphae of Aspergillus species.

Read more about Micafungin

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