Active Ingredient: Pirfenidone
Pirfenidone is indicated in adults for the treatment of idiopathic pulmonary fibrosis (IPF).
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 267 milligrams pirfenidone, 3 times daily, over the duration of 7 days. Afterwards, oral, 534 milligrams pirfenidone, 3 times daily, over the duration of 7 days. Afterwards, oral, 801 milligrams pirfenidone, 3 times daily.
Upon initiating treatment, the dose should be titrated to the recommended daily dose of 2403 mg/day over a 14-day period as follows:
The recommended maintenance daily dose of pirfenidone is 801 mg three times a day with food for a total of 2403 mg/day.
Doses above 2403 mg/day are not recommended for any patient.
Patients who miss 14 consecutive days or more of pirfenidone treatment should re-initiate therapy by undergoing the initial 2-week titration regimen up to the recommended daily dose.
It should be taken with food to reduce the possibility of nausea and dizziness.
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