Active Ingredient: Macitentan
Macitentan, as monotherapy or in combination, is indicated for the long-term treatment of pulmonary arterial hypertension (PAH) in adult patients and in paediatric patients aged less than 18 years and bodyweight ≥40 kg with of WHO Functional Class (FC) II to III).
For this indication, competent medicine agencies globally authorize below treatments:
For:
In case that patient weight is ≥ 40 kg
Oral, 10 milligrams macitentan, once daily.
The recommended dose is 10 mg once daily. Macitentan should be taken every day at about the same time.
If the patient misses a dose of macitentan, the patient should be told to take it as soon as possible and then take the next dose at the regularly scheduled time. The patient should be told not to take two doses at the same time if a dose has been missed.
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