Paroxysmal ventricular arrhythmia

Active Ingredient: Flecainide

Indication for Flecainide

Population group: only adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Treatment of severe symptomatic and life-threatening paroxysmal ventricular arrhythmia which has failed to respond to other forms of therapy or where other treatments have not been tolerated.

For this indication, competent medicine agencies globally authorize below treatments:

200-400 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

200 - 400 mg

Dosage regimen

From 100 To 200 mg 2 time(s) per day every day

Detailed description

The recommended starting dose is 100mg twice daily. The maximum daily dose is 400mg and this is normally reserved for patients of large build or where rapid control of the arrhythmia is required. After 3-5 days it is recommended that the dosage be progressively adjusted to the lowest level which maintains control of the arrhythmia. It may be possible to reduce dosage during long term treatment.

Dosage considerations

In order to avoid the possibility of food affecting the absorption of the drug, flecainide should be taken on an empty stomach or one hour before food.

1-5 mg/kg

Route of admnistration

Intravenous

Defined daily dose

1.5 - 5 mg per kg of body weight

Dosage regimen

From 1.5 To 5 mg per kg of body weight once every day

Loading dose

1 mg per kg of body weight

Active ingredient

Flecainide

Flecainide acetate is a Class IC antiarrhythmic agent used for the treatment of severe symptomatic life-threatening ventricular arrhythmias and supraventricular arrhythmias. Electrophysiologically, flecainide is a local anaesthetic-type (Class IC) of antiarrhythmic compound. It is an amide type of local anaesthetic, being structurally related to procainamide and encainide in so far as these agents are also benzamide derivatives.

Read more about Flecainide

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