Otitis externa, prurigo nodularis, insect bite reactions

Active Ingredient: Clobetasone

Indication for Clobetasone

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Clobetasone is a moderately potent topical corticosteroid indicated for adults, elderly, children and infants for the relief of the inflammatory and pruritic manifestations of steroid responsive dermatoses.

These include the following:

  • Otitis externa
  • Prurigo nodularis
  • Insect bite reactions

Clobetasone may be used as maintenance therapy between courses of one of the more potent topical steroids.

For this indication, competent medicine agencies globally authorize below treatments:

1-4 spreads daily

Route of admnistration

Cutaneous

Defined daily dose

1 - 4 {spreads}

Dosage regimen

From 0.25 To 1 {spreads} 4 time(s) per day every day

Detailed description

Creams are especially appropriate for moist or weeping surfaces.

Apply thinly and gently rub in using only enough to cover the entire affected area once or twice a day until improvement occurs, then reduce the frequency of application or change the treatment to a less potent preparation. Allow adequate time for absorption after each application before applying an emollient.

Therapy with topical corticosteroids should be gradually discontinued once control is achieved and an emollient continued as maintenance therapy.

Rebound of pre-existing dermatoses can occur with abrupt discontinuation of topical corticosteroids especially with potent preparations.

Duration of treatment for adults and elderly

Continuous daily treatment for longer than four weeks is not recommended. If the condition worsens or does not improve within four weeks, treatment and diagnosis should be re-evaluated.

Paediatric population

Use in children under 12 years should be on the advice of a doctor.

Care should be taken when using clobetasone to ensure the amount applied is the minimum that provides therapeutic benefit.

Duration of treatment for children and infants

When clobetasone is used in the treatment of dermatoses in children, extreme caution is required and treatment should not normally exceed 7 days.

If the condition worsens or does not improve within 7 days, treatment should be reviewed.

Once the condition has been controlled, the frequency of application should be reduced to the lowest effective dose for the shortest time possible.

Continuous daily treatment for longer than 4 weeks is not recommended in children.

Elderly

Clinical studies have not identified differences in responses between the elderly and younger patients. The greater frequency of decreased hepatic or renal function in the elderly may delay elimination if systemic absorption occurs. Therefore the minimum quantity should be used for the shortest duration to achieve the desired clinical benefit.

Active ingredient

Clobetasone

Clobetasone is a topical corticosteroids. Clobetasone has little effect on hypothalamo-pituitary-adrenal function. Clobetasone is less potent than other available corticosteroid preparations and has been shown not to suppress the hypothalamo-pituitary-adrenal axis in patients treated for psoriasis or eczema.

Read more about Clobetasone

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