For this indication, competent medicine agencies globally authorize below treatments:
4 - 8 g
From 1 To 2 g 4 time(s) per day every day
Severe attacks: 1 to 2 g four times a day may be given in conjunction with steroids as part of an intensive management regime. Rapid passage of the suspension may reduce the effect of the drug.
The night time interval between doses should not exceed 8 hours.
2 - 2 g
From 1 To 1 g 2 time(s) per day every day
The dose is adjusted according to the severity of the disease and the patient’s tolerance of the drug.
Two suppositories of 0.5g are to be inserted in the morning and two at bedtime after defecation. After three weeks the dosage is gradually reduced as improvement occurs.
In severe generalised ulcerative colitis of the rectum or recto sigmoid, or in cases who are responding slowly to oral therapy, one or two suppositories may be given in the morning and at bedtime additional to oral therapy.