Unstable angina, non-Q wave myocardial infarction

Active Ingredient: Dalteparin

Indication for Dalteparin

Population group: only adults (18 years old or older)

Unstable angina and non-Q wave myocardial infarction (unstable coronary artery disease-UCAD), administered concurrently with aspirin.

Patients needing treatment beyond 8 days, while awaiting angiography/revascularisation, should receive a fixed dose of either 5,000 IU (women <80 kg and men <70 kg) or 7,500 IU (women ≥80 kg and men ≥70 kg) 12 hourly. Treatment is recommended to be given until the day of the revascularisation procedure (PTCA or CA BG) but not for more than 45 days.

For this indication, competent medicine agencies globally authorize below treatments:

240 IU/kg in 2 divided doses daily

Route of admnistration

Subcutaneous

Defined daily dose

240 - 240 [iU] per kg of body weight

Dosage regimen

From 120 To 120 [iU] per kg of body weight 2 time(s) per day every day

Detailed description

120 IU/kg body weight are administered subcutaneously 12 hourly for up to 8 days if considered of benefit by the physician. Maximum dose is 10,000 IU/12 hours.

Active ingredient

Dalteparin

Dalteparin is an antithrombotic agent, which acts mainly through its ability to potentiate the inhibition of Factor Xa and thrombin by antithrombin. It has a relatively higher ability to potentiate Factor Xa inhibition than to prolong plasma clotting time (APTT).

Read more about Dalteparin

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