Erectile dysfunction

Active Ingredient: Tadalafil

Indication for Tadalafil

Population group: men, only adults (18 years old or older)

Treatment of erectile dysfunction in adult males. In order for tadalafil to be effective, sexual stimulation is required.

For this indication, competent medicine agencies globally authorize below treatments:

2.5-20 mg once a day

Route of admnistration

Oral

Defined daily dose

2.5 - 20 mg

Dosage regimen

From 2.5 To 20 mg once every day

Detailed description

In general, the recommended dose is 10 mg taken prior to anticipated sexual activity and with or without food.

In those patients in whom tadalafil 10 mg does not produce an adequate effect, 20 mg might be tried. It may be taken at least 30 minutes prior to sexual activity. The maximum dose frequency is once per day. Tadalafil 10 and 20 mg is intended for use prior to anticipated sexual activity and it is not recommended for continuous daily use.

In patients who anticipate a frequent use of tadalafil (i.e. at least twice weekly) a once daily regimen with the lowest doses of tadalafil might be considered suitable, based on patient choice and the physician’s judgement.

In these patients the recommended dose is 5 mg taken once a day at approximately the same time of day. The dose may be decreased to 2.5 mg once a day based on individual tolerability.

The appropriateness of continued use of the daily regimen should be reassessed periodically.

Dosage considerations

Should be taken prior to anticipated sexual activity and with or without food.

Active ingredient

Tadalafil

Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). When sexual stimulation causes the local release of nitric oxide, inhibition of PDE5 by tadalafil produces increased levels of cGMP in the corpus cavernosum. This results in smooth muscle relaxation and inflow of blood into the penile tissues, thereby producing an erection. Tadalafil has no effect in the absence of sexual stimulation.

Read more about Tadalafil

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