For reduction of blood pressure in essential hypertension. Onset of action of Pindolol is usually rapid, most patients showing a response within the first one to two weeks of treatment. However, maximum response may take several weeks to develop.
For this indication, competent medicine agencies globally authorize below treatments:
10 - 45 mg
From 3.333 To 15 mg 3 time(s) per day every day
Initially 5 mg two or three times a day. According to the response of the patient the dose may be increased at weekly intervals to a maximum of 45 mg given in divided doses twice or three times daily.
Further work shows that many patients respond to a once daily dosage regime. Initially 15 mg should be taken once a day with breakfast and adjusted according to individual response up to a maximum of 45 mg. Most patients respond to a once daily dose of between 15-30 mg.
Patients not responding after three to four weeks at this dosage level rarely benefit from further elevations in dosage. Addition of pindolol to existing diuretic therapy increases the hypotensive effect and combination with other antihypertensives enables reduction in dosage of these agents.