Clostridioides difficile infection (CDI)

Active Ingredient: Fidaxomicin

Indication for Fidaxomicin

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Fidaxomicin is indicated for the treatment of Clostridioides difficile infections (CDI) also known as C. difficile-associated diarrhoea (CDAD) in paediatric patients with a body weight of at least 12.5 kg.

For this indication, competent medicine agencies globally authorize below treatments:

400 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

400 - 400 mg

Dosage regimen

From 200 To 200 mg 2 time(s) per day every day for 10 day(s)

Detailed description

The recommended dose in paediatric patients weighing at least 12.5 kg is 200 mg administered twice daily (once every 12 hours) for 10 days using the film-coated tablets or the granules for oral suspension.

Dosage considerations

It can be taken with or without food.

Active ingredient

Fidaxomicin

Fidaxomicin is an antibiotic belonging to the macrocyclic class of antibacterials. Fidaxomicin is bactericidal and inhibits RNA synthesis by bacterial RNA polymerase. It interferes with RNA polymerase at a distinct site from that of rifamycins. Fidaxomicin is indicated for the treatment of Clostridioides difficile infections (CDI) also known as C. difficile-associated diarrhoea (CDAD) in adult and paediatric patients.

Read more about Fidaxomicin

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