Whipworm, pinworm, threadworm, roundworm, common hookworm, American hookworm

Active Ingredient: Mebendazole

Indication for Mebendazole

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Therapeutic intent: Curative procedure

For the treatment of Trichuris trichuria (whipworm), Enterobius vermicularis (pinworm or threadworm), Ascaris lumbricoides (roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed gastrointestinal infestations.

For this indication, competent medicine agencies globally authorize below treatments:

100 mg twice a day for 3 days

Dosage regimens

Oral, 100 milligrams mebendazole, 2 times daily, over the duration of 3 days.

Detailed description

For the control of trichuriasis, ascariasis and hookworm infections, 100 mg twice a day for three consecutive days.

Mebendazole has not been extensively studied in children below the age of 2 years.

Active ingredient

Mebendazole

In vitro and in vivo work suggests that mebendazole blocks the uptake of glucose by adult and larval forms of helminths, in a selective and irreversible manner. Inhibition of glucose uptake appears to lead to endogenous depletion of glycogen stores within the helminth. Lack of glycogen leads to decreased formation of ATP and ultrastructural changes in the cells.

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