Mild to moderate coronavirus disease 2019 (COVID-19)

Active Ingredient: Molnupiravir

Indication for Molnupiravir

Population group: only adults (18 - 65 years old)

Molnupiravir is indicated for treatment of mild to moderate coronavirus disease 2019 (COVID-19) in adults with a positive SARS-COV-2 diagnostic test and who have at least one risk factor for developing severe illness.

For this indication, competent medicine agencies globally authorize below treatments:

1600 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

1,600 - 1,600 mg

Dosage regimen

From 800 To 800 mg 2 time(s) per day every day for 5 day(s)

Detailed description

The recommended dose of molnupiravir is 800 mg taken orally every 12 hours for 5 days.

The safety and efficacy of molnupiravir when administered for periods longer than 5 days have not been established.

Molnupiravir should be administered as soon as possible after a diagnosis of COVID-19 has been made and within 5 days of symptom onset.

Missed dose

If the patient misses a dose of molnupiravir within 10 hours of the time it is usually taken, the patient should take as soon as possible and resume the normal dosing schedule. If a patient misses a dose by more than 10 hours, the patient should not take the missed dose and instead take the next dose at the regularly scheduled time. The patient should not double the dose to make up for a missed dose.

Dosage considerations

It can be taken with or without food.

Active ingredient

Molnupiravir

Molnupiravir is indicated for treatment of mild to moderate coronavirus disease 2019 (COVID-19) in adults with a positive SARS-COV-2 diagnostic test and who have at least one risk factor for developing severe illness. Molnupiravir is a prodrug that is metabolised to the ribonucleoside analogue N-hydroxycytidine (NHC) which distributes into cells where it is phosphorylated to form the pharmacologically active ribonucleoside triphosphate (NHC-TP).

Read more about Molnupiravir

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