Active Ingredient: Biperiden
For this indication, competent medicine agencies globally authorize below treatments:
Regimen A: Intramuscular, between 10 milligrams biperiden and 20 milligrams biperiden, divided daily.
Regimen B: Intravenous, between 10 milligrams biperiden and 20 milligrams biperiden, divided daily.
At the beginning of treatment and in severe cases, 10-20 mg biperiden can be administered intramuscularly or slowly intravenously, divided into several single doses over the day.
Oral, 1 milligrams biperiden, 2 times daily, over the duration of 2 days. Afterwards, oral, between 2 milligrams biperiden and 16 milligrams biperiden, divided daily. The maximum allowed total dose is 16 milligrams biperiden daily.
Initially 2 times 1 mg (2 mg biperiden hydrochloride/day) distributed over the day. The dose can be increased daily by 2 mg. As maintenance dose, 3–4 times daily 1–4 mg (corresponding to 3–16 mg/day) are administered. The maximum daily dose amounts to 16 mg biperiden hydrochloride.
Should be taken with sufficient liquid preferably during or after a meal.
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