HIV-1 infection

Active Ingredient: Fosamprenavir

Indication for Fosamprenavir

Population group: only adults (18 - 65 years old)

Fosamprenavir in combination with low dose ritonavir is indicated for the treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infected adults and adolescents in combination with other antiretroviral medicinal products.

For this indication, competent medicine agencies globally authorize below treatments:

1400 mg in 2 divided doses daily

Route of admnistration


Defined daily dose

1,400 - 1,400 mg

Dosage regimen

From 700 To 700 mg 2 time(s) per day every day

Detailed description

The recommended dose is 700 mg fosamprenavir twice daily with 100 mg ritonavir twice daily.

Dosage considerations

Fosamprenavir can be taken with or without food.

Active ingredient


Fosamprenavir after oral administration, is rapidly and almost completely hydrolysed to amprenavir and inorganic phosphate prior to reaching the systemic circulation. Amprenavir binds to the active site of HIV-1 protease and thereby prevents the processing of viral gag and gag-pol polyprotein precursors, resulting in the formation of immature noninfectious viral particles.

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