Tuberculosis

Active Ingredient: Isoniazid

Indication for Isoniazid

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

200-300 mg once daily

Route of admnistration

Intravenous

Defined daily dose

200 - 300 mg

Dosage regimen

From 200 To 300 mg once every day

Detailed description

The usual intramuscular or intravenous dose for adults is 200 to 300 mg as a single daily dose, for children 100 to 300 mg daily (10-20 mg/kg), but doses much larger than these are sometimes given, especially in conditions such as tuberculous meningitis. It is recommended to give an intravenous dose slowly as an undiluted bolus injection, although other methods may be employed.

The elderly

No dosage reduction is necessary in the elderly.

200-300 mg once daily

Route of admnistration

Intramuscular

Defined daily dose

200 - 300 mg

Dosage regimen

From 200 To 300 mg once every day

Detailed description

The usual intramuscular or intravenous dose for adults is 200 to 300 mg as a single daily dose, for children 100 to 300 mg daily (10-20 mg/kg), but doses much larger than these are sometimes given, especially in conditions such as tuberculous meningitis. It is recommended to give an intravenous dose slowly as an undiluted bolus injection, although other methods may be employed.

The elderly

No dosage reduction is necessary in the elderly.

50-250 mg once

Route of admnistration

Intrapleural

Defined daily dose

50 - 250 mg

Dosage regimen

From 50 To 250 mg once every day

Detailed description

50 to 250 mg may be instilled intrapleurally after aspiration of pus, the dosage of oral isoniazid on that day being correspondingly reduced. The ampoule solution is also used for the local treatment of tuberculous ulcers, for irrigation of fistulae, etc.

Active ingredient

Isoniazid

Isoniazid is used mainly in the treatment of pulmonary tuberculosis but it appears to be effective also in the treatment of extrapulmonary lesions, including meningitis and genito-urinary disease.

Read more about Isoniazid

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