Treatment of adult patients with primary pulmonary hypertension, classified as NYHA functional class III, to improve exercise capacity and symptoms.
For this indication, competent medicine agencies globally authorize below treatments:
15 - 45 ug
From 2.5 To 7.5 ug 6 time(s) per day every day
At initiation of iloprost treatment the first inhaled dose should be 2.5 microgram iloprost as delivered at the mouthpiece of the nebuliser. If this dose is well tolerated, dosing should be increased to 5 microgram iloprost and maintained at that dose. In case of poor tolerability of the 5 microgram dose, the dose should be reduced to 2.5 microgram iloprost.
The dose per inhalation session should be administered 6 to 9 times per day according to the individual need and tolerability.
The duration of treatment depends on clinical status and is left to the physician’s discretion. Should patients deteriorate on this treatment intravenous prostacyclin treatment should be considered.
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