Symptomatic treatment of nausea and vomiting

Active Ingredient: Metoclopramide

Indication for Metoclopramide

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

10-30 mg in 1-3 divided doses daily

Route of admnistration

Intravenous

Defined daily dose

10 - 30 mg

Dosage regimen

From 3.333 To 10 mg 3 time(s) per day every day for 5 day(s)

Detailed description

For the symptomatic treatment of nausea and vomiting, including acute migraine induced nausea and vomiting and for the prevention of radiotherapy induced nausea and vomiting (RINV): the recommended single dose is 10mg, repeated up to three times daily.

The maximum recommended daily dose is 30mg or 0.5mg/kg body weight.

The injectable treatment duration should be as short as possible and transfer to oral or rectal treatment should be made as soon as possible.

Dosage considerations

Intravenous doses should be administered as a slow bolus (at least over 3 minutes).

0.1-0.5 mg/kg in 1-3 divided doses daily

Route of admnistration

Intravenous

Defined daily dose

0.1 - 0.5 mg per kg of body weight

Dosage regimen

From 0.033 To 0.167 mg per kg of body weight 3 time(s) per day every day for 5 day(s)

Detailed description

For the symptomatic treatment of nausea and vomiting, including acute migraine induced nausea and vomiting and for the prevention of radiotherapy induced nausea and vomiting (RINV): the recommended single dose is 10mg, repeated up to three times daily.

The maximum recommended daily dose is 30mg or 0.5mg/kg body weight.

The injectable treatment duration should be as short as possible and transfer to oral or rectal treatment should be made as soon as possible.

Dosage considerations

Intravenous doses should be administered as a slow bolus (at least over 3 minutes).

10-30 mg in 1-3 divided doses daily

Route of admnistration

Oral

Defined daily dose

10 - 30 mg

Dosage regimen

From 3.333 To 10 mg 3 time(s) per day every day for 5 day(s)

Detailed description

The recommended single dose is 10 mg, repeated up to three times daily.

The maximum recommended daily dose is 30 mg or 0.5mg/kg body weight.

The maximum recommended treatment duration is 5 days.

Active ingredient

Metoclopramide

The action of metoclopramide is closely associated with parasympathetic nervous control of the upper gastro-intestinal tract where it has the effect of encouraging normal peristaltic action. This provides for a fundamental approach to the control of those conditions where disturbed gastrointestinal motility is a common underlying factor.

Read more about Metoclopramide

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