Hypertension

Active Ingredient: Guanabenz

Indication for Guanabenz

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Guanabenz is indicated in the treatment of hypertension. It may be employed alone or in combination with a thiazide diuretic.

For this indication, competent medicine agencies globally authorize below treatments:

4 mg twice daily and followed by increases in increments of 4 to 8 mg per day every one to two weeks, depending on the patient's response

For:

Dosage regimens

Oral, 4 milligrams guanabenz, 2 times daily. Afterwards, oral, between 8 milligrams guanabenz and 32 milligrams guanabenz, divided daily. The maximum allowed total dose is 32 milligrams guanabenz daily.

Detailed description

Dosage with guanabenz should be individualized. A starting dose of 4 mg twice a day is recommended, whether guanabenz is used alone or with a thiazide diuretic. Dosage may be increased in increments of 4 to 8 mg per day every one to two weeks, depending on the patient’s response. The maximum dose studied to date has been 32 mg twice daily, but doses as high as this are rarely needed.

Active ingredient

Guanabenz

Guanabenz is an orally active central alpha-2 adrenergic agonist. Its antihypertensive action appears to be mediated via stimulation of central alpha adrenergic receptors, resulting in a decrease of sympathetic outflow from the brain at the bulbar level to the peripheral circulatory system.

Read more about Guanabenz

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