Benign prostatic hyperplasia (BPH)

Active Ingredient: Finasteride

Indication for Finasteride

Population group: men, only adults (18 years old or older)
Therapeutic intent: Curative procedure

Finasteride is indicated for the treatment and control of benign prostatic hyperplasia (BPH) in patients with an enlarged prostate to:

  • cause regression of the enlarged prostate, improve urinary flow and improve the symptoms associated with BPH
  • reduce the incidence of acute urinary retention and the need for surgery including transurethral resection of the prostate (TURP) and prostatectomy.

For this indication, competent medicine agencies globally authorize below treatments:

5 mg once daily


Dosage regimens

Oral, 5 milligrams finasteride, once daily.

Detailed description

The recommended adult dose is one 5 mg tablet daily, with or without food. Finasteride can be administered alone or in combination with the alpha-blocker doxazosin. Although early improvement in symptoms may be seen, treatment for at least six months may be necessary to assess whether a beneficial response has been achieved. Thereafter, treatment should be continued long term.

Dosage considerations

Should be taken with or without food.

Active ingredient


Finasteride is a competitive inhibitor of human 5α-reductase, an intracellular enzyme which metabolises testosterone into the more potent androgen, dihydrotestosterone (DHT). In benign prostatic hyperplasia (BPH), enlargement of the prostate gland is dependent upon the conversion of testosterone to DHT within the prostate. Finasteride is highly effective in reducing circulating and intraprostatic DHT. Finasteride has no affinity for the androgen receptor.

Read more about Finasteride

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