Deep vein thrombosis (DVT), pulmonary embolism (PE)

Indication for Enoxaparin

Population group: Suitable for both men and women, only adults (18 years old or older)

Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), excluding PE likely to require thrombolytic therapy or surgery.

For this indication, competent medicine agencies globally authorize below treatments:

150 IU/kg once daily

Route of admnistration

Subcutaneous

Defined daily dose

150 - 150 [iU] per kg of body weight

Dosage regimen

From 150 To 150 [iU] per kg of body weight once every day

Detailed description

Enoxaparin sodium can be administered SC either as a once daily injection of 150 IU/kg (1.5 mg/kg) or as twice daily injections of 100 IU/kg (1 mg/kg).

The regimen should be selected by the physician based on an individual assessment including evaluation of the thromboembolic risk and of the risk of bleeding. The dose regimen of 150 IU/kg (1.5 mg/kg) administered once daily should be used in uncomplicated patients with low risk of VTE recurrence. The dose regimen of 100 IU/kg (1 mg/kg) administered twice daily should be used in all other patients such as those with obesity, with symptomatic PE, cancer, recurrent VTE or proximal (vena iliaca) thrombosis.

Enoxaparin sodium treatment is prescribed for an average period of 10 days. Oral anticoagulant therapy should be initiated when appropriate.

Dosage considerations

Injection should be made preferably when the patient is lying down. Enoxaparin sodium is administered by deep SC injection.

The administration should be alternated between the left and right anterolateral or posterolateral abdominal wall.

150 IU/kg once daily

Route of admnistration

Subcutaneous

Defined daily dose

1.5 - 1.5 mg per kg of body weight

Dosage regimen

From 1.5 To 1.5 mg per kg of body weight once every day

Detailed description

Enoxaparin sodium can be administered SC either as a once daily injection of 150 IU/kg (1.5 mg/kg) or as twice daily injections of 100 IU/kg (1 mg/kg).

The regimen should be selected by the physician based on an individual assessment including evaluation of the thromboembolic risk and of the risk of bleeding. The dose regimen of 150 IU/kg (1.5 mg/kg) administered once daily should be used in uncomplicated patients with low risk of VTE recurrence. The dose regimen of 100 IU/kg (1 mg/kg) administered twice daily should be used in all other patients such as those with obesity, with symptomatic PE, cancer, recurrent VTE or proximal (vena iliaca) thrombosis.

Enoxaparin sodium treatment is prescribed for an average period of 10 days. Oral anticoagulant therapy should be initiated when appropriate.

Dosage considerations

Injection should be made preferably when the patient is lying down. Enoxaparin sodium is administered by deep SC injection.

The administration should be alternated between the left and right anterolateral or posterolateral abdominal wall.

200 IU/kg in 2 divided doses daily

Route of admnistration

Subcutaneous

Defined daily dose

200 - 200 [iU] per kg of body weight

Dosage regimen

From 100 To 100 [iU] per kg of body weight 2 time(s) per day every day

Detailed description

Enoxaparin sodium can be administered SC either as a once daily injection of 150 IU/kg (1.5 mg/kg) or as twice daily injections of 100 IU/kg (1 mg/kg).

The regimen should be selected by the physician based on an individual assessment including evaluation of the thromboembolic risk and of the risk of bleeding. The dose regimen of 150 IU/kg (1.5 mg/kg) administered once daily should be used in uncomplicated patients with low risk of VTE recurrence. The dose regimen of 100 IU/kg (1 mg/kg) administered twice daily should be used in all other patients such as those with obesity, with symptomatic PE, cancer, recurrent VTE or proximal (vena iliaca) thrombosis.

Enoxaparin sodium treatment is prescribed for an average period of 10 days. Oral anticoagulant therapy should be initiated when appropriate.

Dosage considerations

Injection should be made preferably when the patient is lying down. Enoxaparin sodium is administered by deep SC injection.

The administration should be alternated between the left and right anterolateral or posterolateral abdominal wall.

2 mg/kg in 2 divided doses daily

Route of admnistration

Subcutaneous

Defined daily dose

2 - 2 mg per kg of body weight

Dosage regimen

From 1 To 1 mg per kg of body weight 2 time(s) per day every day

Detailed description

Enoxaparin sodium can be administered SC either as a once daily injection of 150 IU/kg (1.5 mg/kg) or as twice daily injections of 100 IU/kg (1 mg/kg).

The regimen should be selected by the physician based on an individual assessment including evaluation of the thromboembolic risk and of the risk of bleeding. The dose regimen of 150 IU/kg (1.5 mg/kg) administered once daily should be used in uncomplicated patients with low risk of VTE recurrence. The dose regimen of 100 IU/kg (1 mg/kg) administered twice daily should be used in all other patients such as those with obesity, with symptomatic PE, cancer, recurrent VTE or proximal (vena iliaca) thrombosis.

Enoxaparin sodium treatment is prescribed for an average period of 10 days. Oral anticoagulant therapy should be initiated when appropriate.

Dosage considerations

Injection should be made preferably when the patient is lying down. Enoxaparin sodium is administered by deep SC injection.

The administration should be alternated between the left and right anterolateral or posterolateral abdominal wall.

Active ingredient

Enoxaparin is a LMWH with a mean molecular weight of approximately 4,500 daltons, in which the antithrombotic and anticoagulant activities of standard heparin have been dissociated. The drug substance is the sodium salt and has a high anti-Xa activity.

Read more about Enoxaparin

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