Active Ingredient: Cladribine
Cladribine is indicated for the treatment of hairy cell leukaemia.
For this indication, competent medicine agencies globally authorize below treatments:
Subcutaneous
0.14 - 0.14 mg per kg of body weight
From 0.14 To 0.14 mg per kg of body weight once every day for 5 day(s)
The recommended posology for hairy cell leukaemia is a single course of cladribine given by subcutaneous bolus injection at a daily dose of 0.14 mg/kg body weight for 5 consecutive days.
Deviations from the posology indicated above are not advised.
Experience with patients older than 65 years is limited. Elderly patients should be treated by individual assessment and careful monitoring of the blood counts and of the renal and hepatic function. The risk requires assessment on a case-by-case basis.
Intravenous
0.09 - 0.09 mg per kg of body weight
From 0.09 To 0.09 mg per kg of body weight once every day for 7 day(s)
The recommended treatment for Hairy Cell Leukaemia is a single course of cladribine given by continuous intravenous infusion for 7 consecutive days at a dose of 0.09 mg/kg/day (3.6 mg/m²/day). Deviations from this dosage regimen are not advised. Physicians should consider delaying or discontinuing the drug if neurotoxicity or renal toxicity occurs.
Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.
